Forschungsbericht 2018



Extremozyme

Institut: V-7
Projektleitung: Garabed Antranikian
Stellvertretende Projektleitung: Anna Krüger
Laufzeit: 01.01.2016 — 31.01.2021

Identifizierung, Produktion und Charakterisierung robuster Biokatalysatoren aus extremophilen Mikroorganismen für die Anwendung in nachhaltigen, biotechnologischen Prozessen

Publikationen

  • Elleuche S., Schröder C., Stahlberg N., Antranikian G.: "Boiling Water is not too Hot for Us!" - Preferred Living Spaces of Heat-Loving Microbes. Front Young Minds, 5(1), 2017.
  • Elleuche, Skander; Esselun, Petra; Grote, Ralf; Klippel, Barbara; Krüger, Anna; Liese, Andreas; Ostrop, Margit; Schäfers, Christian; Schröder, Carola; Antranikian, Garabed: 8th International Congress on Biocatalysis (Biocat2016), Hamburg, Germany, 28 August–1 September, 2016 (Meeting Report). Catalysts 2016, 6(160), 2016. , DOI: 10.3390/catal6100160
  • Hilterhaus, Lutz; Liese, Andreas; Kettling, Ulrich; Antranikian, Garabed: Applied Biocatalysis: From Fundamental to Industrial Applications. Wiley-VCH Verlag GmbH, , 2016
  • Schröder C., Burkhardt C., Busch P., Schirrmacher G., Claren J. and Antranikian G.: Characterization of a Theme C Glycoside Hydrolase Family 9 Endo-Beta-Glucanase from a Biogas Reactor Metagenome. The Protein Journal, 2018.
  • Schröder C., Janzer V.A., Schirrmacher G., Claren J., Antranikian G.: Characterization of two novel heat-active α-galactosidases from thermophilic bacteria. Extremophiles, 21(1): S. 85-94, 2017. , DOI: 10.1007/s00792-016-0885-z
  • Schäfers C., Blank S., Wiebusch S., Elleuche S., Antranikian G.: Complete genome sequence of Thermus brockianus GE-1 reveals key enzymes of xylan/xylose metabolism. Standards in Genomic Sciences, 12(22), 2017. , DOI: 10.1186/s40793-017-0225-7
  • Ibrahim, Abdelnasser S. S.; El-Toni, Ahmed M.; Al-Salamah, Ali A.; Almaary, Khalid S.; El-Tayeb, Mohamed A.; Elbadawi, Yahya B.; Antranikian, Garabed: Development of novel robust nanobiocatalyst for detergents formulations and the other applications of alkaline protease. Bioprocess and Biosystems Engineering, 39: S. 793–805, 2016. , DOI: 10.1007/s00449-016-1559-z
  • Antranikian G., Suleiman M., Schäfers C., Adams M.W.W., Bartolucci S., Blamey J.M., Birkeland N.K., Bonch-Osmolovskaya E., da Costa M.S., Cowan D., Danson M., Forterre P., Kelly R., Ishino Y., Littlechild J., Moracci M., Noll K., Oshima T., Robb F., Rossi M., Santos H., Schönheit P., Sterner R., Thauer R., Thomm M., Wiegel J., Stetter K.O.: Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island. Extremophiles, 2017. , DOI: 10.1007/s00792-017-0938-y
  • Ibrahim, Abdelnasser S. S.; Al-Salamah, Ali A.; El-Toni, Ahmed M.; Almaary, Khalid S.; El-Tayeb, Mohamed A.; Elbadawi, Yahya B.; Antranikian, Garabed: Enhancement of alkaline protease activity and stability via covalent immobilization onto hollow core-mesoporous shell silica nanospheres. International Journal of Molecular Sciences, 17: S. 184, 2016. , DOI: 10.3390/ijms17020184
  • Suleiman M., Schröder C., Klippel B., Schäfers C., Krüger A. and Antranikian G.: Extremely thermoactive archaeal endoglucanase from a shallow marine hydrothermal vent from Vulcano Island. Applied Microbiology and Biotechnology, 2018.
  • Antranikian, Garabed: Foreword. In Rampelotto; Pabulo H., Hrsg., Grand Challenges in Biology and Biotechnology , S. vii-viii. Springer Verlag, 2016.
  • Rizk, Mazen, Antranikian, Garabed, Elleuche, Skander: Influence of linker length variations on the biomass-degrading performance of heat-active enzyme chimeras. Molecular Biotechnology, 58: S. 268-279, 2016. , DOI: 10.1007/s12033-016-9925-2
  • Antranikian G.: International Conference on Extremophiles 2016. Extremophiles, 21(1): S. 1-2, 2017. , DOI: 10.1007/s00792-016-0906-y
  • Elleuche, Skander; Schröder, Carola; Antranikian, Garabed: Lipolytic Extremozymes from Psychro- and (Hyper-)Thermophilic Prokaryotes and their Potential for Industrial Applications. In Rampelotto; Pabulo H., Hrsg., Grand Challenges in Biology and Biotechnology , S. 351-374. Springer Verlag, 2016.
  • Elleuche S., Krull A., Lorenz U., Antranikian G.: Parallel N- and C-Terminal Truncations Facilitate Purification and Analysis of a 155-kDa Cold-Adapted Type-I Pullulanase. Protein J, 2017. , DOI: 10.1007/s10930-017-9703-4
  • Krüger, Anna; Elleuche, Skander; Sahm, Kerstin; Antranikian, Garabed: Robust biocataysts - routes to new diversity. In Hilterhaus, Lutz; Liese, Andreas; Kettling, Ulrich; Antranikian, Garabed, Hrsg., Applied Biocatalysis: From Fundamental Science to Industrial Applications , S. 31-51. Wiley-VCH Verlag GmbH, 2016.
  • Krüger A., Schäfers C., Schröder C., Antranikian G.: Towards a sustainable biobased industry – Highlighting the impact of extremophiles. New Biotechnology, 2018. , DOI: 10.1016/j.nbt.2017.05.002